Download fasta file
Blue: basic residues (KRH); red: acidic residues (DE); purple: amides (QN); black: hydrophobic residues (AVLIPWFM); green: polar (CSTYG) (http://weblogo.berkeley.edu/)
| 5.3 | Class: SAND domain factors (SAND) | |
| Description: | Class description: A twisted beta-sheet exposes four alpha-helices that are packed against one side of the sheet. Most important for DNA-binding is a KDWK motif at the N-terminus of the third alpha-helix. Residues of this alpha-helix and the KWDK motif contact bases through the major groove, but the alpha-helix does not insert into the major groove. The domain structure of some of the class members is supported by an overlaying zinc coordinating motif. (PMID 11427895, PMID 15649886) | |
| Aligned domain sequences: | Alignment of SAND domains Download fasta file |
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| Logo plot: | Blue: basic residues (KRH); red: acidic residues (DE); purple: amides (QN); black: hydrophobic residues (AVLIPWFM); green: polar (CSTYG) (http://weblogo.berkeley.edu/) |
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